SR-16435

SR-16435 is a drug which acts as a potent partial agonist at both the μ-opioid receptor and nociceptin receptor. In animal studies it was found to be a potent analgesic, with results suggestive of reduced development of tolerance and increased activity against neuropathic pain compared to classic μ-selective agonists.^[1][2][3]

SR-16435

Identifiers
IUPAC name 1-[1-(9-bicyclo[3.3.1]nonanyl)piperidin-4-yl]-3H-indol-2-one
CAS Number	857262-16-9
PubChem CID	11461888
Chemical and physical data
Formula	C22H30N2O
Molar mass	338.495 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CC2CCCC(C1)C2N3CCC(CC3)N4C(=O)CC5=CC=CC=C54
InChI InChI=1S/C22H30N2O/c25-21-15-18-5-1-2-10-20(18)24(21)19-11-13-23(14-12-19)22-16-6-3-7-17(22)9-4-8-16/h1-2,5,10,16-17,19,22H,3-4,6-9,11-15H2 Key:XVFXJQGBDPFCRF-UHFFFAOYSA-N

See also

• Cebranopadol
• Brorphine
• J-113,397
• SR-14968
• SR-17018