SLC22A10

Solute carrier family 22 member 10 (SLC22A10), also known as organic anion transporter 5 (OAT5), is a protein that in humans is encoded by the SLC22A10 gene.^[3][4]

SLC22A10
Identifiers
Aliases	SLC22A10, OAT5, hOAT5, solute carrier family 22 member 10
External IDs	OMIM: 607580; HomoloGene: 111144; GeneCards: SLC22A10; OMA:SLC22A10 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.3 Start 63,268,022 bp[1] End 63,311,783 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in liver right lobe of liver testicle gonad superior frontal gyrus primary visual cortex Brodmann area 9 right frontal lobe cingulate gyrus anterior cingulate cortex n/a More reference expression data BioGPS n/a
Gene ontology Molecular function sodium-independent organic anion transmembrane transporter activity transmembrane transporter activity inorganic anion exchanger activity urate transmembrane transporter activity Cellular component integral component of membrane integral component of plasma membrane membrane plasma membrane Biological process sodium-independent organic anion transport transmembrane transport inorganic anion transport urate transport organic anion transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 387775 n/a Ensembl ENSG00000184999 n/a UniProt Q63ZE4 n/a RefSeq (mRNA) NM_001039752 n/a RefSeq (protein) NP_001034841 n/a Location (UCSC) Chr 11: 63.27 – 63.31 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

References

1. GRCh38: Ensembl release 89: ENSG00000184999 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: solute carrier family 22".
4. Sun W; Wu RR; van Poelje PD; Erion MD (May 2001). "Isolation of a family of organic anion transporters from human liver and kidney". Biochem. Biophys. Res. Commun. 283 (2): 417–22. doi:10.1006/bbrc.2001.4774. PMID 11327718.

Further reading

• Wang AG, Yoon SY, Oh JH, et al. (2006). "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags". Biochem. Biophys. Res. Commun. 345 (3): 1022–32. doi:10.1016/j.bbrc.2006.04.175. PMID 16712791.
• Eraly SA; Nigam SK (2002). "Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters". Biochem. Biophys. Res. Commun. 297 (5): 1159–66. doi:10.1016/S0006-291X(02)02343-4. PMID 12372408.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. Bibcode:2006Natur.440..497T. doi:10.1038/nature04632. PMID 16554811.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.