RBM11

Splicing regulator RBM11 is a protein that is encoded by the RBM11 gene^[5][6] in humans.

RBM11
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2YWK
Identifiers
Aliases	RBM11, RNA binding motif protein 11
External IDs	OMIM: 617937; MGI: 2447622; HomoloGene: 16988; GeneCards: RBM11; OMA:RBM11 - orthologs
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q11.2 Start 14,216,130 bp[1] End 14,228,372 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C3.1 Start 75,389,732 bp[2] End 75,399,717 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis C1 segment testicle gonad oocyte tibial nerve left ovary Brodmann area 9 prefrontal cortex secondary oocyte Top expressed in lumbar spinal ganglion spermatocyte embryo dentate gyrus of hippocampal formation granule cell embryo facial motor nucleus seminiferous tubule primary visual cortex ganglion of neuraxis superior frontal gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleic acid binding protein binding protein homodimerization activity RNA binding poly(U) RNA binding single-stranded RNA binding Cellular component nuclear speck nucleus nucleoplasm Biological process multicellular organism development cellular response to oxidative stress mRNA processing cell differentiation regulation of alternative mRNA splicing, via spliceosome RNA splicing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54033 224344 Ensembl ENSG00000185272 ENSMUSG00000032940 UniProt P57052 Q80YT9 RefSeq (mRNA) NM_144770 NM_001320602 NM_198302 RefSeq (protein) NP_001307531 NP_658983 NP_938044 Location (UCSC) Chr 21: 14.22 – 14.23 Mb Chr 16: 75.39 – 75.4 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000185272 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032940 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Gardiner K, Slavov D, Bechtel L, Davisson M (May 2002). "Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysis". Genomics. 79 (6): 833–43. doi:10.1006/geno.2002.6782. PMID 12036298.
6. "Entrez Gene: RBM11 RNA binding motif protein 11".

Further reading

• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. Bibcode:2000Natur.405..311H. doi:10.1038/35012518. PMID 10830953.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.