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Vaccine candidate against COVID-19 From Wikipedia, the free encyclopedia
QazCovid-in, commercially known as QazVac,[1][2] is a COVID-19 vaccine developed by the Research Institute for Biological Safety Problems in Kazakhstan.[3][4] QazCoVac-P is a second COVID-19 vaccine developed by the Kazakh Biosafety Research Institute and in clinical trials.[5]
| Vaccine description | |
|---|---|
| Target | SARS-CoV-2 |
| Vaccine type | Inactivated |
| Clinical data | |
| Routes of administration | Intramuscular |
| Identifiers | |
| CAS Number |
|
| DrugBank | |
The vaccine can be stored at standard refrigeration temperatures (2 °C-8 °C) and is a two-dose régime with the doses administered twenty-one days apart.[6] The vaccine was first manufactured by Kazakhstan's Research Institute of Biological Safety Problems. Production capacity has been capped at 50,000 doses per month.[citation needed]
Beginning in June 2021, the vaccine is slated[7] to be packaged in large bulk to be bottled in Turkey by a major Turkish company.[8] This will allow for a production capacity of 500,000-600,000 doses per month.[9] The contract is still being negotiated,[10] despite earlier claims suggesting that the deal had already been finalized.[11][12]
In October 2021, it was announced that the vaccine would be supplied to Afghanistan and other countries in 2022.[13]
In September 2020, QazVac started in Phase I/II clinical trials.[14]
In December 2020, QazVac is currently in Phase III clinical trials, which is expected to be fully completed by 9 July 2021.[2][8] It is unclear when the first preliminary results will be published.[15][12]
The administration of the vaccine for the general population began at the end of April 2021.[16] The Research Institute Kunsulu Zakarya's Director General's justification is that the trial is almost 50% completed and "people who have received [the] vaccine feel well; there have been no side-effects and the effectiveness of the vaccine is high".[8]
In September 2021, a study was published to eClinicalMedicine, published by The Lancet. The study’s findings were that the “QazCovid-in® vaccine was safe and well-tolerated and induced predominantly mild adverse events; no serious or severe adverse events were recorded in both trials.” [17]
The first batch of 50,000 doses was delivered on 26 April 2021, and vaccination began shortly after.[citation needed] In June 2021, the capacity will increase to 100,000 doses per month, regardless of the contract for bottling in Turkey.[18]
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