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QKI

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QKI
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Quaking homolog, KH domain RNA binding (mouse), also known as QKI, is a protein which in humans is encoded by the QKI gene.[5][6]

Quick Facts Available structures, PDB ...

QKI belongs to a family of RNA-binding proteins called STAR proteins for Signal Transduction and Activation of RNA.[7] They have an HNRNPK homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1) and SF1 .[8] Two more new members are KHDRBS3[9] and KHDRBS2.[10]

The QKI gene is implicated as being important in schizophrenia,[11][12] and QKI controls translation of many oligodendrocyte-related genes.

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