Pyridoxiphen

Pyridoxiphen
Clinical data
Other names	Amphetamine–pyridoxine condensation product; Phenamine–pyridoxine condensation product; Pyridoxyphen; Pyridoxiphene; Piridoksifen; Piridoksifena; Pyridoxylamphetamine
Identifiers
	IUPAC name 4-(hydroxymethyl)-2-methyl-5-[(1-phenylpropan-2-ylamino)methyl]pyridin-3-ol;
PubChem CID	121419;
ChemSpider	108374;
Chemical and physical data
Formula	C17H22N2O2
Molar mass	286.375 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=NC=C(C(=C1O)CO)CNC(C)CC2=CC=CC=C2;
	InChI InChI=1S/C17H22N2O2/c1-12(8-14-6-4-3-5-7-14)18-9-15-10-19-13(2)17(21)16(15)11-20/h3-7,10,12,18,20-21H,8-9,11H2,1-2H3; Key:UDDSBCOQRRHWBZ-UHFFFAOYSA-N;

Pyridoxiphen, also known as amphetamine–pyridoxine condensation product or as pyridoxylamphetamine, is a drug of the substituted amphetamine family which was developed in the Soviet Union in the 1960s.^[1]^[2]^[3]^[4]^[5]^[6] It is the condensation product of amphetamine (phenamine) and pyridoxine (vitamin B₆).^[2] It was developed for potential treatment of central nervous system conditions.^[2] The drug has sympatholytic and hypotensive effects in animals.^[7]^[1]^[6]^[8] It is highly ionic and may not be able to cross the blood–brain barrier.^[7]

Quick Facts Clinical data, Other names ...

Close

See also