PSTPIP1

Proline-serine-threonine phosphatase-interacting protein 1 is an enzyme that in humans is encoded by the PSTPIP1 gene.^[5][6]

PSTPIP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DIL
Identifiers
Aliases	PSTPIP1, CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP, proline-serine-threonine phosphatase interacting protein 1
External IDs	OMIM: 606347; MGI: 1321396; HomoloGene: 37867; GeneCards: PSTPIP1; OMA:PSTPIP1 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q24.3 Start 76,993,359 bp[1] End 77,037,475 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 B Start 55,997,246 bp[2] End 56,036,172 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte monocyte blood spleen bone marrow cells lymph node appendix tendon of biceps brachii Achilles tendon upper lobe of left lung Top expressed in granulocyte thymus blood stroma of bone marrow mesenteric lymph nodes molar tibiofemoral joint primary oocyte gastric mucosa mucous cell of stomach More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding identical protein binding cytoskeletal protein binding actin filament binding Cellular component cytoplasm perinuclear region of cytoplasm cytosol plasma membrane uropod cleavage furrow cell projection cytoskeleton membrane lamellipodium actin filament Biological process cell adhesion inflammatory response endocytosis signal transduction immune system process innate immune response actin filament polymerization cell migration Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9051 19200 Ensembl ENSG00000140368 ENSMUSG00000032322 UniProt O43586 P97814 RefSeq (mRNA) NM_003978 NM_001321135 NM_001321136 NM_001321137 NM_011193 RefSeq (protein) NP_001308064 NP_001308065 NP_001308066 NP_003969 NP_035323 Location (UCSC) Chr 15: 76.99 – 77.04 Mb Chr 9: 56 – 56.04 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

PSTPIP1 has been shown to interact with:

• Abl gene^[7]
• BZW1^[8]
• CD2^[5]
• PTPN12^[9]
• PTPN18^[10]
• Wiskott–Aldrich syndrome protein^[11]

See also

• PAPA syndrome