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Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
PAX-interacting protein 1 is a protein that in humans is encoded by the PAXIP1 gene.[5][6]
This gene is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis.[6] Protein-affecting variants have also been implicated in Alzheimer's disease.[7]
PAXIP1 has been shown to interact with PAX2[8] and TP53BP1.[9][10]
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