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Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
Protein OS-9 is a protein that in humans is encoded by the OS9 gene.[5][6][7][8][9]
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[9]
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