O-4310

O-4310 (1-isopropyl-6-fluoro-psilocin) is a tryptamine derivative developed by Organix Inc which acts as a serotonin receptor agonist. It is claimed to have an EC₅₀ of 5 nM at the 5-HT_2A receptor with 89% efficacy relative to serotonin, and 100-fold selectivity over the 5-HT_2C receptor, while being apparently inactive at the 5-HT_2B antitarget.^[1][2]

O-4310

Clinical data
Other names	1-Isopropyl-6-fluoro-psilocin
Identifiers
IUPAC name 3-[2-(dimethylamino)ethyl]-6-fluoro-1-isopropyl-1H-indol-4-ol
CAS Number	885671-63-6 Y
PubChem CID	68541087
ChemSpider	65322014
UNII	EJ3AE64233
CompTox Dashboard (EPA)	DTXSID001045394
Chemical and physical data
Formula	C15H21FN2O
Molar mass	264.344 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)N1C2=CC(F)=CC(O)=C2C(CCN(C)C)=C1
InChI InChI=1S/C15H21FN2O/c1-10(2)18-9-11(5-6-17(3)4)15-13(18)7-12(16)8-14(15)19/h7-10,19H,5-6H2,1-4H3 Key:PAUIFMSQKOHMQT-UHFFFAOYSA-N

See also

• 1-Methylpsilocin
• 5-Fluoro-DMT
• Psilocin
• SCHEMBL5334361
• 7-F-5-MeO-MET

References

1. US 7655691, Kumaran G, Morency C, Roth B, Sard HP, Shuster L Xu L, "Indole compounds useful as serotonin selective agents.", published 11 May 2006, assigned to Organix Inc
2. Motaghinejad O, Motaghinejad M, Motevalian M, Rahimi-Sharbaf F, Beiranvand T (October 2017). "The effect of maternal forced exercise on offspring pain perception, motor activity and anxiety disorder: the role of 5-HT2 and D2 receptors and CREB gene expression". Journal of Exercise Rehabilitation. 13 (5): 514–525. doi:10.12965/jer.1734992.496. PMC 5667597. PMID 29114525.