NUFIP1

Nuclear fragile X mental retardation-interacting protein 1 is a protein that in humans is encoded by the NUFIP1 gene.^[5][6][7]

NUFIP1
Identifiers
Aliases	NUFIP1, NUFIP, bA540M5.1, FMR1 interacting protein 1, nuclear FMR1 interacting protein 1, Rsa1
External IDs	OMIM: 604354; MGI: 1351474; HomoloGene: 8216; GeneCards: NUFIP1; OMA:NUFIP1 - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q14.12 Start 44,939,249 bp[1] End 44,989,471 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 D3 Start 76,348,331 bp[2] End 76,374,819 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell gonad secondary oocyte ventricular zone testicle ganglionic eminence Brodmann area 23 gastrocnemius muscle Achilles tendon islet of Langerhans Top expressed in primitive streak epiblast renal corpuscle medullary collecting duct external carotid artery Gonadal ridge internal carotid artery Paneth cell abdominal wall endothelial cell of lymphatic vessel More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding ATPase binding identical protein binding protein-macromolecule adaptor activity snoRNA binding RNA binding metal ion binding DNA binding nucleic acid binding Cellular component nuclear matrix nucleus pre-snoRNP complex perichromatin fibrils nucleolus cytosolic ribosome transcription elongation factor complex fibrillar center presynaptic active zone protein-containing complex synapse Biological process box C/D snoRNP assembly positive regulation of transcription by RNA polymerase II RNA processing protein complex oligomerization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26747 27275 Ensembl ENSG00000083635 ENSMUSG00000022009 UniProt Q9UHK0 Q9QXX8 RefSeq (mRNA) NM_012345 NM_013745 RefSeq (protein) NP_036477 NP_038773 Location (UCSC) Chr 13: 44.94 – 44.99 Mb Chr 14: 76.35 – 76.37 Mb PubMed search [3] [4]
Wikidata
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Interactions

NUFIP1 has been shown to interact with:

• BRCA1,^[8]
• Cyclin T1,^[8] and
• FMR1.^[5][9]