Mopeia virus
Species of virus From Wikipedia, the free encyclopedia
Mopeia virus (MOPV) is a species of virus in the genus Mammarenavirus.[1] It was initially isolated from the Mastomys natalensis mouse in the East African country of Mozambique in 1977.[2][3][4] It is of the "Old World" Arenavirus lineage and is closely related to Lassa mammarenavirus, sharing 75% of its amino acid sequence.[5][6]
| Mopeia virus | |
|---|---|
| Virus classification | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Negarnaviricota |
| Class: | Bunyaviricetes |
| Order: | Hareavirales |
| Family: | Arenaviridae |
| Genus: | Mammarenavirus |
| Species: | Mammarenavirus mopeiaense |
| Strains | |
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| Synonyms | |
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Mopeia virus disease
Mopeia virus has not been known to cause disease in humans, although it is capable of infecting human cell lines in vitro.[7] Infection of primates with the virus was demonstrated to prevent clinical disease following Lassa virus infection, indicating potential for use as a prophylactic vaccine for Lassa Fever.[8]
Geographic distribution
Although initially isolated in Mozambique, it has also been detected in rodents in Zimbabwe,[9] and Tanzania.[4]
References
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