Metheptazine

Metheptazine is an opioid analgesic from the phenazepane family. It was developed by American Home Products in the 1950s.^[1]

Metheptazine

Clinical data
Other names	Metheptazine
ATC code	none
Identifiers
IUPAC name methyl 1,2-dimethyl-4-phenylazepane-4-carboxylate
CAS Number	469-78-3 Y
PubChem CID	3047717
ChemSpider	2310051 Y
UNII	93X4R66P5A
ChEMBL	ChEMBL2104520 N
CompTox Dashboard (EPA)	DTXSID10861967
Chemical and physical data
Formula	C16H23NO2
Molar mass	261.365 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(OC)C2(c1ccccc1)CC(N(C)CCC2)C
InChI InChI=1S/C16H23NO2/c1-13-12-16(15(18)19-3,10-7-11-17(13)2)14-8-5-4-6-9-14/h4-6,8-9,13H,7,10-12H2,1-3H3 Y Key:RAAFYFKWMRWOIT-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Metheptazine produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.

Metheptazine is not listed as a controlled substance under the Controlled Substances Act 1970 in the United States.^[2] The Canadian Controlled Drugs and Substances Act specifically excludes the Phenazepine opioids Metheptazine, Ethoheptazine, and Metethoheptazine from control.

References

1. US 3316244, Bell SC, Childress SJ, "Process for the preparation of hexahydro-1,3-dimethyl-4-phenylazepine-4-carboxylic acid, ethyl ester", issued 25 April 1967, assigned to American Home Products Corporation.
2. "Conversion Factors for Controlled Substances". U.S. Department of Justice, Drug Enforcement Administration, Diversion Control Division.