Meclinertant

Meclinertant (SR-48692) is a drug which acts as a selective, non-peptide antagonist at the neurotensin receptor NTS₁, and was the first non-peptide antagonist developed for this receptor.^[1][2] It is used in scientific research to explore the interaction between neurotensin and other neurotransmitters in the brain,^{[3][4][5][6][7][8]} and produces anxiolytic, anti-addictive and memory-impairing effects in animal studies.^{[9][10][11][12]}

Meclinertant

Identifiers
IUPAC name 2-([1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carbonyl]amino)adamantane-2-carboxylic acid
CAS Number	146362-70-1 Y
PubChem CID	119192
IUPHAR/BPS	1582
UNII	5JBP4SI96H
ChEMBL	ChEMBL506981
CompTox Dashboard (EPA)	DTXSID40163360
Chemical and physical data
Formula	C32H31ClN4O5
Molar mass	587.07 g·mol−1
3D model (JSmol)	Interactive image
SMILES c7cc3c(cc7Cl)nccc3-n4nc(cc4-c1c(OC)cccc1OC)C(=O)NC2(C(O)=O)C5CC(C6)CC2CC6C5
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