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McArdle or MacArdle is an Irish surname. It originates in County Monaghan, where it was the fifth most common surname in 1970. The surname in Irish is MacArdghail, from ardghal, meaning 'high valour' or from the Irish "ardghail" meaning "tall foreigner" with roots "ard" meaning "tall" and "gail" meaning "foreigner", indicative of their original ancestor being a Viking or from Viking stock. The surname is also common in County Armagh and County Louth.
They are a branch of the McMahon clans of Oriel, descendants from 'Ardghail Mor MacMahon' (Irish name: Ardghail MacBriain MacMathghamhna), who was chief of the MacMahons and King of Oriel from 1402 to 1416. They were based originally in the barony of Monaghan and a branch became sub-chiefs in County Armagh under the O'Neills of the Fews.[1][2][3]
- Aidan McArdle, Irish actor
- Andrea McArdle, Irish-American singer and actress
- Angela McArdle, American Libertarian politician
- Brian McArdle (1911–2002), British doctor
- J. Brian De Largie McArdle (1920–1969), Australian photojournalist, editor of Walkabout magazine
- Charlotte McArdle, Chief Nursing Officer for Northern Ireland
- Donald Macardle, Irish actor and writer
- Dorothy Macardle, Irish author and historian
- Fiachra McArdle, Irish footballer for Kildare F.C
- Harry McArdle, British scientist
- Jack McArdle, British Designer
- James McArdle, Scottish actor
- John McArdle (born 1949), English actor
- John J. McArdle, American psychologist
- Joseph A. McArdle, Pennsylvania legislator
- Kenndal McArdle, Canadian ice hockey player
- L. D. McArdle, American politician
- Mark McArdle, Queensland legislator
- Mary McArdle, Irish biographer and revolutionary
- Megan McArdle, Washington-based blogger and journalist
- Nick McArdle, Australian sportscaster
- Pete McArdle, Irish-American long-distance runner
- Peter McArdle, English artist
- Peter McArdle (footballer) (1914–79), English footballer
- Rory McArdle, football player for Northern Ireland and Rochdale A.F.C.
- Stanley McArdle (1922–2007), British Rear Admiral in the Royal Navy
- McArdle Laboratory
- McArdle's disease, a metabolic disease more often known as glycogen storage disease type V
- Macardle Moore Brewery
- McCardle
- James MacArdell
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