Mapp Biopharmaceutical
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Mapp Biopharmaceutical is an American pharmaceutical company founded in 2003 by Larry Zeitlin and Kevin Whaley.[2] Mapp Biopharmaceutical is based in San Diego, California. It is responsible for the research and development of ZMapp, a drug which is still[when?] under development and comprises three humanized monoclonal antibodies used as a treatment for Ebola virus disease.[3][4] The drug was first tested in humans during the 2014 West Africa Ebola virus outbreak.
| Headquarters | , |
|---|---|
Key people | Larry Zeitlin (President) Kevin Whaley (CEO)[1] |
| Products | Biopharmaceuticals |
| Subsidiaries | LeafBio |
| Website | mappbio |
The ZMapp drug is a result of the collaboration between Mapp Biopharmaceutical, LeafBio (the commercial arm of Mapp Biopharmaceutical),[5] Defyrus Inc. (Toronto), the U.S. government, and the Public Health Agency of Canada.[3] The antibody work came out of research projects funded by Defense Advanced Research Projects Agency (DARPA) more than a decade ago,[1] and years of funding by the Public Health Agency of Canada.[6] ZMapp is manufactured in the tobacco plant Nicotiana benthamiana in the bioproduction process known as "pharming" by Kentucky BioProcessing, a subsidiary of Reynolds American.[7][8][9]
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