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MT-7716 is an experimental opioid drug that could potentially be used in the treatment of alcohol addiction.
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| Names | |
|---|---|
| IUPAC name
2-[3-[1-[(1R)-1,2-Dihydroacenaphthylen-1-yl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]-N-methylacetamide | |
| Identifiers | |
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PubChem CID |
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CompTox Dashboard (EPA) |
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| Properties | |
| C27H28N4O2 | |
| Molar mass | 440.547 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Unlike most opioids, MT-7716 does not appear to act through delta, kappa and mu opioid receptors, but instead is an agonist of the nociceptin receptor.[1]
A study has shown that MT-7716 was able to decrease alcohol self-administration and reduce alcohol withdrawal symptoms in rats.[2]
Another study was also able to show similar results, in addition to demonstrating MT-7716's ability to suppress stress-induced alcohol seeking.[3]
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