MAST1

Microtubule-associated serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MAST1 gene.^[5]

MAST1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2M9X, 3PS4
Identifiers
Aliases	MAST1, SAST, SAST170, microtubule associated serine/threonine kinase 1, MCCCHCM
External IDs	OMIM: 612256; MGI: 1861901; HomoloGene: 10543; GeneCards: MAST1; OMA:MAST1 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.13 Start 12,833,951 bp[1] End 12,874,952 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8 C3|8 41.32 cM Start 85,638,532 bp[2] End 85,663,988 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum right frontal lobe ganglionic eminence anterior cingulate cortex Brodmann area 9 paraflocculus of cerebellum prefrontal cortex frontal pole Brodmann area 10 anterior pituitary Top expressed in motor neuron cerebellar cortex central gray substance of midbrain superior colliculus pontine nuclei ventromedial nucleus primary visual cortex dorsomedial hypothalamic nucleus dorsal tegmental nucleus cerebellar vermis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding magnesium ion binding metal ion binding kinase activity Cellular component cytoplasm plasma membrane intracellular anatomical structure cytoskeleton membrane Biological process protein phosphorylation intracellular signal transduction cytoskeleton organization peptidyl-serine phosphorylation phosphorylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22983 56527 Ensembl ENSG00000105613 ENSMUSG00000053693 UniProt Q9Y2H9 Q9R1L5 RefSeq (mRNA) NM_014975 NM_019945 RefSeq (protein) NP_055790 NP_064329 Location (UCSC) Chr 19: 12.83 – 12.87 Mb Chr 8: 85.64 – 85.66 Mb PubMed search [3] [4]
Wikidata
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