This is a list of editors-in-chief of the largest newspapers in Canada by circulation.
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- Mark Harrison (1977–1989)
- Norman Webster (1989–1993)
- Joan Fraser (1993–1996)
- Alan Allnutt (1996–2000)
- Peter Stockland (2000–2004)
- Andrew Phillips (2004–2009)
- Raymond Brassard (2010–2013)
- Lucinda Chodan (2013–present)
- André Lecompte (1964–?)
- Paule Beaugrand-Champagne
- Lyne Robitaille
- Peter Worthington (1971–1982), editor until 1976; no editor-in-chief previously
- Barbara Amiel (1983–1985)
- John Downing (1985–1997), with the title of editor; there was no editor-in-chief until 1995
- Peter O'Sullivan (1995–1999)
- Mike Strobel (1999–2001)
- Mike Therien (2001–2004)
- Jim Jennings (2004–2006)
- Glenn Garnett (2007)
- Lou Clancy (2007–2009)
- James Wallace (2009–2013)
- Wendy Metcalfe (2013–2015)
- Adrienne Batra (2015–present)
- William Fisher Luxton (1872–1893)
- Frederick Molyneux St. John (1893–1895)
- Arnott James Magurn (1898–1901)
- John Wesley Dafoe (1901–1944)
- George Victor Ferguson (1944–1946)
- Grant Dexter (1946–1954)
- Thomas Worrall Kent (1954–1959)
- Shane MacKay (1959–1967)
- Richard S. Malone (1967–1974)
- Peter McLintock (1974–1979)
- John Dafoe (1979–1993)
- Duncan McMonagle (1993–1996)
- Nicholas Hirst (1996–2005)
- Bob Cox (2005–2007)
- Margo Goodhand (2007–2012)
- Paul Samyn (2012–present)