Large neutral amino acids transporter small subunit 3

Large neutral amino acids transporter small subunit 3 is a protein that in humans is encoded by the SLC43A1 gene.^[5][6][7]

SLC43A1
Identifiers
Aliases	SLC43A1, LAT3, PB39, POV1, R00504, solute carrier family 43 member 1
External IDs	OMIM: 603733; MGI: 1931352; HomoloGene: 2688; GeneCards: SLC43A1; OMA:SLC43A1 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 57,484,534 bp[1] End 57,515,780 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 D Start 84,838,850 bp[2] End 84,863,594 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas right lobe of liver gastric mucosa body of stomach right ovary left ovary gallbladder gonad muscle of thigh stromal cell of endometrium Top expressed in muscle of thigh tail of embryo genital tubercle thymus embryo yolk sac human fetus ventricular zone bone marrow spleen More reference expression data BioGPS More reference expression data
Gene ontology Molecular function neutral amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity amino acid transmembrane transporter activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process amino acid transport neutral amino acid transport transmembrane transport amino acid transmembrane transport L-alpha-amino acid transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8501 72401 Ensembl ENSG00000149150 ENSMUSG00000027075 UniProt O75387 Q8BSM7 RefSeq (mRNA) NM_001198810 NM_003627 NM_001081349 NM_001083809 NM_024497 RefSeq (protein) NP_001185739 NP_003618 NP_001074818 NP_001077278 NP_078773 Location (UCSC) Chr 11: 57.48 – 57.52 Mb Chr 2: 84.84 – 84.86 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• SLC43A1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

References

1. GRCh38: Ensembl release 89: ENSG00000149150 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027075 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Chuaqui RF, Englert CR, Strup SE, Vocke CD, Zhuang Z, Duray PH, Bostwick DG, Linehan WM, Liotta LA, Emmert-Buck MR (Sep 1997). "Identification of a novel transcript up-regulated in a clinically aggressive prostate carcinoma". Urology. 50 (2): 302–7. doi:10.1016/S0090-4295(97)00194-5. PMID 9255310.
6. Cole KA, Chuaqui RF, Katz K, Pack S, Zhuang Z, Cole CE, Lyne JC, Linehan WM, Liotta LA, Emmert-Buck MR (Nov 1998). "cDNA sequencing and analysis of POV1 (PB39): a novel gene up-regulated in prostate cancer". Genomics. 51 (2): 282–7. doi:10.1006/geno.1998.5359. PMID 9722952.
7. "Entrez Gene: SLC43A1 solute carrier family 43, member 1".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Babu E, Kanai Y, Chairoungdua A, et al. (2003). "Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters". J. Biol. Chem. 278 (44): 43838–45. doi:10.1074/jbc.M305221200. PMID 12930836.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Skotheim RI, Monni O, Mousses S, et al. (2002). "New insights into testicular germ cell tumorigenesis from gene expression profiling". Cancer Res. 62 (8): 2359–64. PMID 11956097.
• Shuangshoti S, Viratchai C (1976). "Encephalomalacia unrelated to vascular occlusion". Journal of the Medical Association of Thailand = Chotmaihet Thangphaet. 59 (9): 421–5. PMID 972295.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.