LGD-2226

Chemical compound From Wikipedia, the free encyclopedia

LGD-2226

LGD-2226 is an investigational selective androgen receptor modulator (SARM),[1] which is being developed for treatment of muscle wasting and osteoporosis.[2]

Quick Facts Legal status, Identifiers ...
LGD-2226
Thumb
Legal status
Legal status
Identifiers
  • 6-(bis-(2,2,2-trifluoroethyl)amino)-4-trifluoromethyl-1H-quinolin-2-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.230.470 Edit this at Wikidata
Chemical and physical data
FormulaC14H9F9N2O
Molar mass392.225 g·mol−1
3D model (JSmol)
  • FC(F)(F)c(c2)c1cc(N(CC(F)(F)F)CC(F)(F)F)ccc1[nH]c2=O
  • InChI=1S/C14H9F9N2O/c15-12(16,17)5-25(6-13(18,19)20)7-1-2-10-8(3-7)9(14(21,22)23)4-11(26)24-10/h1-4H,5-6H2,(H,24,26)
  • Key:ULBPQWIGZUGPHU-UHFFFAOYSA-N
  (verify)
Close

LGD-2226 is an orally active, potent and selective agonist for androgen receptors which was shown to have anabolic effects in both muscle and bone tissue, but with considerably less effects on prostate weight and luteinizing hormone levels than testosterone.[3][4]

Selective androgen receptor modulators may also be used by athletes to assist in training and increase physical stamina and fitness, potentially producing effects similar to anabolic steroids but with significantly less side effects. For this reason, SARMs have already been banned by the World Anti-Doping Agency since January 2008 despite no drugs from this class yet being in clinical use, and blood tests for all known SARMs are currently being developed,[5][6] including LGD-2226.[7]

References

Wikiwand in your browser!

Seamless Wikipedia browsing. On steroids.

Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.

Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.