KLF10

Krueppel-like factor 10 is a protein that in humans is encoded by the KLF10 gene.^[5][6][7]

KLF10
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2EPA
Identifiers
Aliases	KLF10, EGR-alpha, EGRA, TIEG, TIEG1, Kruppel-like factor 10, Kruppel like factor 10
External IDs	OMIM: 601878; MGI: 1101353; HomoloGene: 4135; GeneCards: KLF10; OMA:KLF10 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q22.3 Start 102,648,784 bp[1] End 102,655,725 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 B3.1 Start 38,291,707 bp[2] End 38,300,950 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of paranasal sinus skin of hip skin of thigh germinal epithelium gastric mucosa synovial joint parietal pleura saphenous vein lactiferous duct human penis Top expressed in spermatocyte gastrula urothelium urinary bladder transitional epithelium of urinary bladder left lung lobe renal corpuscle stria vascularis muscle of thigh plantaris muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding DNA-binding transcription factor activity metal ion binding protein binding nucleic acid binding core promoter sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process skeletal system development bone mineralization cellular response to peptide regulation of transcription, DNA-templated somatic stem cell population maintenance rhythmic process cell-cell signaling positive regulation of osteoclast differentiation negative regulation of transcription by RNA polymerase II transcription, DNA-templated circadian rhythm cell population proliferation transforming growth factor beta receptor signaling pathway negative regulation of cell population proliferation cellular response to starvation regulation of circadian rhythm negative regulation of transcription, DNA-templated transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7071 21847 Ensembl ENSG00000155090 ENSMUSG00000037465 UniProt Q13118 O89091 RefSeq (mRNA) NM_001032282 NM_005655 NM_001289471 NM_013692 NM_001357677 RefSeq (protein) NP_001027453 NP_005646 NP_001276400 NP_038720 NP_001344606 Location (UCSC) Chr 8: 102.65 – 102.66 Mb Chr 15: 38.29 – 38.3 Mb PubMed search [3] [4]
Wikidata
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See also

• Kruppel-like factors