Isopropyl acetate

Isopropyl acetate is an ester, an organic compound which is the product of esterification of acetic acid and isopropanol. It is a clear, colorless liquid with a characteristic fruity odor.^[3]

Isopropyl acetate

Names
IUPAC name Propan-2-yl acetate
Systematic IUPAC name Propan-2-yl ethanoate
Other names Isopropyl acetate 2-Acetoxypropane 2-Propyl acetate 2-Propyl ethanoate Propan-2-yl ethanoate
Identifiers
CAS Number	108-21-4 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1608674
ChemSpider	7627 Y
ECHA InfoCard	100.003.238
EC Number	203-561-1
PubChem CID	7915
RTECS number	AI4930000
UNII	1Y67AFK870 Y
UN number	1220
CompTox Dashboard (EPA)	DTXSID2025478
InChI InChI=1S/C5H10O2/c1-4(2)7-5(3)6/h4H,1-3H3 N Key: JMMWKPVZQRWMSS-UHFFFAOYSA-N N InChI=1/C5H10O2/c1-4(2)7-5(3)6/h4H,1-3H3 Key: JMMWKPVZQRWMSS-UHFFFAOYAA
SMILES CC(OC(C)C)=O
Properties
Chemical formula	C5H10O2
Molar mass	102.133 g·mol−1
Density	0.87 g/cm3
Melting point	−73 °C (−99 °F; 200 K)
Boiling point	89 °C (192 °F; 362 K)
Solubility in water	4.3 g/100 mL (27 °C), 3.0 g/100 mL (20 °C)
Vapor pressure	42 mmHg (20 °C)[1]
Magnetic susceptibility (χ)	−67.04·10−6 cm3/mol
Hazards
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H225, H319, H336
Precautionary statements	P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+P361+P353, P304+P340, P305+P351+P338, P312, P337+P313, P370+P378, P403+P233, P403+P235, P405, P501
NFPA 704 (fire diamond)	1 3
Flash point	2 °C (36 °F; 275 K)
Autoignition temperature	460 °C (860 °F; 733 K)
Explosive limits	1.8–7.8%
Lethal dose or concentration (LD, LC):
LC50 (median concentration)	11,918 ppm (rat, 8 hr)[2]
NIOSH (US health exposure limits):
PEL (Permissible)	TWA 250 ppm (950 mg/m3)[1]
REL (Recommended)	None established[1]
IDLH (Immediate danger)	1800 ppm[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Isopropyl acetate is a solvent with a wide variety of manufacturing uses that is miscible with most other organic solvents, and slightly soluble in water (although less so than ethyl acetate). It is used as a solvent for cellulose, plastics, oil and fats. It is a component of some printing inks^[4] and perfumes.

Isopropyl acetate decomposes slowly on contact with steel in the presence of air, producing acetic acid and isopropanol. It reacts violently with oxidizing materials and it attacks many plastics.^[5]

Isopropyl acetate is quite flammable in both its liquid and vapor forms, and it may be harmful if swallowed or inhaled.^[6]

The Occupational Safety and Health Administration has set a permissible exposure limit (PEL) of 250 ppm (950 mg/m³) over an eight-hour time-weighted average for workers handling isopropyl acetate.^[7]

References

1. NIOSH Pocket Guide to Chemical Hazards. "#0358". National Institute for Occupational Safety and Health (NIOSH).
2. "Isopropyl acetate". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
3. "Isopropyl acetate". ChemViP. Archived from the original on 2012-07-15. Retrieved 2009-04-20.
4. "Celanese - The chemistry inside innovation™". chemvip.com. Archived from the original on 15 July 2012. Retrieved 18 May 2015.
5. "ISOPROPYL ACETATE". International Chemical Safety Cards. Archived from the original on 2011-07-22. Retrieved 2009-06-25.
6. "Iso-propyl Acetate". Material Safety Data Sheets.
7. "NIOSH Pocket Guide to Chemical Hazards - Isopropyl acetate". Centers for Disease Control and Prevention.