Isocytosine
Chemical compound that is an isomer of cytosine From Wikipedia, the free encyclopedia
Chemical compound that is an isomer of cytosine From Wikipedia, the free encyclopedia
Isocytosine or 2-aminouracil is a pyrimidine base that is an isomer of cytosine. It is used in combination with isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA.[1] In particular, it is used as a nucleobase of hachimoji RNA.[2]
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Names | |
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Preferred IUPAC name
2-Amino-3H-pyrimidin-4-one | |
Other names
2-Aminouracil | |
Identifiers | |
3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.003.266 |
PubChem CID |
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CompTox Dashboard (EPA) |
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Properties | |
C4H5N3O | |
Molar mass | 111.104 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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It can be synthesized from guanidine and malic acid.[3]
It is also used in physical chemical studies involving metal complex binding, hydrogen bonding, and tautomerism and proton transfer effects in nucleobases.[4]
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