Ipidacrine

Chemical compound From Wikipedia, the free encyclopedia

Ipidacrine

Ipidacrine (Neiromidin) is a drug first synthesized by the National Research Center for Biologically Active Compounds in the Russian Federation. This compound is a modification of the older drug tacrine (Cognex).[1]

Quick Facts Clinical data, Trade names ...
Ipidacrine
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Clinical data
Trade namesNeiromidin
Other namesAmiridine; NIK-247
ATC code
Legal status
Legal status
  • US: Unscheduled Not FDA approved
Identifiers
  • 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.201.385
Chemical and physical data
FormulaC12H16N2
Molar mass188.274 g·mol−1
3D model (JSmol)
  • C1CCc2c(c(c3c(n2)CCC3)N)C1
  • InChI=1S/C12H16N2/c13-12-8-4-1-2-6-10(8)14-11-7-3-5-9(11)12/h1-7H2,(H2,13,14)
  • Key:YLUSMKAJIQOXPV-UHFFFAOYSA-N
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Ipidacrine is a reversible acetylcholinesterase inhibitor used in memory disorders of different origins.[2][3][4]

Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.[5]

See also

References

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