Iotalamic acid

Iotalamic acid, sold under the brand name Conray, is an iodine-containing radiocontrast agent. It is available in form of its salts, sodium iotalamate and meglumine iotalamate. It can be given intravenously or intravesically (into the urinary bladder).^[1]

Iotalamic acid

Clinical data
Trade names	Conray, Glofil-125, Cysto-Conray II, others
Other names	MI-216, iothalamate meglumine, Iothalamic acid (USAN US)
AHFS/Drugs.com	Consumer Drug Information
License data	US DailyMed: Iothalamate
Routes of administration	Intravascular[1]
ATC code	V08AA04 (WHO)
Legal status
Legal status	US: ℞-only[1][2][3]
Identifiers
IUPAC name 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
CAS Number	2276-90-6
PubChem CID	3737
DrugBank	DB09133
ChemSpider	3606
UNII	16CHD79MIX
KEGG	D01258
ChEBI	CHEBI:31713
ChEMBL	ChEMBL1201300
CompTox Dashboard (EPA)	DTXSID5023164
ECHA InfoCard	100.017.181
Chemical and physical data
Formula	C11H9I3N2O4
Molar mass	613.916 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I
InChI InChI=1S/C11H9I3N2O4/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20/h1-2H3,(H,15,18)(H,16,17)(H,19,20) Key:UXIGWFXRQKWHHA-UHFFFAOYSA-N

A radioactive formulation is also available as sodium iothalamate I-125 injection (brand name Glofil-125). It is indicated for evaluation of glomerular filtration in the diagnosis or monitoring of people with kidney disease.^[2]

References

1. "Conray- iothalamate meglumine injection". DailyMed. 1 January 2021. Retrieved 23 February 2022.
2. "Glofil-125- sodium iothalamate i-125 injection injection, solution". DailyMed. 9 December 2019. Retrieved 23 February 2022.
3. "Cysto-Conray II- iothalamate meglumine injection". DailyMed. 31 December 2020. Retrieved 23 February 2022.

External links

• "Iothalamate meglumine". Drug Information Portal. U.S. National Library of Medicine.
• "Iothalamate sodium". Drug Information Portal. U.S. National Library of Medicine.