Imidazoquinoline

Imidazoquinoline is a tricyclic organic molecule; its derivatives and compounds are often used for antiviral^[1] and antiallergic^[2] creams.

Imidazoquinoline, and locations of possible modification to form its derivatives. The R1 group should be a N atom with the R1 attached to it.

Derivatives

• Dactolisib
• Imiquimod
• Gardiquimod
• Resiquimod
• Sumanirole

References

1. Hemmi, H; Kaisho, T; Takeuchi, O; Sato, S; Sanjo, H; Hoshino, K; Horiuchi, T; Tomizawa, H; Takeda, K; Akira, S (February 2002). "Small Anti-Viral Compounds Activate Immune Cells Via the TLR7 MyD88-Dependent Signaling Pathway". Nature Immunology. 3 (2): 196–200. doi:10.1038/ni758. PMID 11812998.
2. Peet, NP; Baugh, LE; Sunder, S; Lewis, JE (March 1985). "Synthesis and Antiallergic Activity of Some Quinolinones and Imidazoquinolinones". Journal of Medicinal Chemistry. 28 (3): 298–302. doi:10.1021/jm00381a007. PMID 2857792.