HMGXB3

HMG-box containing 3 is a protein that in humans is encoded by the HMGXB3 gene. ^[5]

HMGXB3
Identifiers
Aliases	HMGXB3, HMGX3, SMF, HMG-box containing 3
External IDs	MGI: 2441817; HomoloGene: 44229; GeneCards: HMGXB3; OMA:HMGXB3 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q32 Start 150,000,046 bp[1] End 150,053,142 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 E1 Start 61,264,349 bp[2] End 61,310,122 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in olfactory bulb stromal cell of endometrium right uterine tube vena cava parotid gland cardia nasal epithelium lateral nuclear group of thalamus pylorus trachea Top expressed in Rostral migratory stream spermatocyte zygote spermatid tail of embryo secondary oocyte substantia nigra retinal pigment epithelium female urethra motor neuron More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding kinase activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus cellular component Biological process phosphorylation biological process regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22993 106894 Ensembl ENSG00000113716 ENSMUSG00000024622 UniProt Q12766 Q562E5 n/a RefSeq (mRNA) NM_014983 NM_001366501 NM_134134 NM_178277 RefSeq (protein) NP_055798 NP_001353430 NP_055798.2 n/a Location (UCSC) Chr 5: 150 – 150.05 Mb Chr 18: 61.26 – 61.31 Mb PubMed search [3] [4]
Wikidata
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Function

This gene is one of the non-canonical high mobility group (HMG) genes. The encoded protein contains an HMG-box domain found in DNA binding proteins such as transcription factors and chromosomal proteins.

References

1. GRCh38: Ensembl release 89: ENSG00000113716 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000024622 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: HMG-box containing 3". Retrieved 2016-03-29.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.