HAUS1

HAUS augmin-like complex subunit 1 is a protein that in humans is encoded by the HAUS1 gene.^[4][5][6]

HAUS1
Identifiers
Aliases	HAUS1, CCDC5, HEI-C, HEIC, HsT1461, HAUS augmin like complex subunit 1
External IDs	OMIM: 608775; MGI: 2385076; HomoloGene: 15516; GeneCards: HAUS1; OMA:HAUS1 - orthologs
Gene location (Mouse) Chr. Chromosome 18 (mouse)[1] Band 18|18 E3 Start 77,757,567 bp[1] End 77,767,780 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence monocyte stromal cell of endometrium rectum Achilles tendon smooth muscle tissue bone marrow gallbladder lymph node appendix Top expressed in spermatid spermatocyte yolk sac testicle epiblast embryo blastocyst embryo ventricular zone bone marrow More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding molecular function Cellular component microtubule organizing center centrosome spindle spindle pole microtubule HAUS complex cytoskeleton cytoplasm cytosol Biological process spindle assembly cell cycle cell division G2/M transition of mitotic cell cycle ciliary basal body-plasma membrane docking centrosome cycle regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 115106 225745 Ensembl n/a ENSMUSG00000041840 UniProt Q96CS2 Q8BHX1 RefSeq (mRNA) NM_138443 NM_146089 NM_001357531 NM_001357532 NM_001357533 RefSeq (protein) NP_612452 NP_666201 NP_001344460 NP_001344461 NP_001344462 Location (UCSC) n/a Chr 18: 77.76 – 77.77 Mb PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCm38: Ensembl release 89: ENSMUSG00000041840 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
5. Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, et al. (May 2009). "HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity". Curr Biol. 19 (10): 816–26. Bibcode:2009CBio...19..816L. doi:10.1016/j.cub.2009.04.033. PMID 19427217. S2CID 2893122.
6. "Entrez Gene: CCDC5 coiled-coil domain containing 5 (spindle associated)".

External links

• Human HAUS1 genome location and HAUS1 gene details page in the UCSC Genome Browser.

Further reading

• Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Einarson MB, Cukierman E, Compton DA, Golemis EA (2004). "Human Enhancer of Invasion-Cluster, a Coiled-Coil Protein Required for Passage through Mitosis". Mol. Cell. Biol. 24 (9): 3957–71. doi:10.1128/MCB.24.9.3957-3971.2004. PMC 387757. PMID 15082789.
• Ramachandran N, Hainsworth E, Bhullar B, Eisenstein S, Rosen B, Lau AY, et al. (2004). "Self-assembling protein microarrays". Science. 305 (5680): 86–90. Bibcode:2004Sci...305...86R. doi:10.1126/science.1097639. PMID 15232106. S2CID 20936301.
• Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.