Goblet cell carcinoid
Medical condition From Wikipedia, the free encyclopedia
Medical condition From Wikipedia, the free encyclopedia
The goblet cell carcinoid (GCC) is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.[1]
| Goblet cell carcinoid | |
|---|---|
| Other names | Crypt cell carcinoma, neuroendocrine tumour with goblet cell differentiation |
| |
| Micrograph showing a goblet cell carcinoid. H&E stain. | |
GCCs may present as appendicitis.
GCCs are diagnosed by pathology. They have a characteristic biphasic appearance which includes (1) goblet cell-like cells, and (2) neuroendocrine-type nuclear chromatin (stippled chromatin).
GCCs have an aggressive course compared to other appendiceal neuroendocrine tumours.[1]
GCCs are treated with surgery.
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