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Globuloviridae is a family of hyperthermophilic archaeal viruses. Crenarchaea of the genera Pyrobaculum and Thermoproteus (both in Thermoproteaceae) serve as natural hosts. There are four species in this family, assigned to a single genus, Alphaglobulovirus.[1][2][3]
| Globuloviridae | |
|---|---|
 | |
Virus classification  | |
| (unranked): | Virus |
| Family: | Globuloviridae |
| Genera | |
| |
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The family contains one genus which contains four species:[3]
- Alphaglobulovirus
- Alphaglobulovirus PSV
- Alphaglobulovirus PSV1
- Alphaglobulovirus TSPV1
- Alphaglobulovirus TTSV1
Virions in the Globuloviridae are spherical and enveloped. The diameter is around 100 nm.[1][2]
Genomes are linear dsDNA and non-segmented, around 20–30kb in length.[1][2]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Alphaglobulovirus | Spherical | Enveloped | Linear | Monopartite |
Viral replication is cytoplasmic. DNA-templated transcription is the method of transcription. Pyrobaculum and Thermoproteus archaea serve as the natural host. Transmission routes are passive diffusion.[1]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Alphaglobulovirus | Pyrobaculum and Thermoproteus archaea | None | Injection | Budding | Cytoplasm | Cytoplasm | Passive diffusion |
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