Giant condyloma acuminatum
Medical condition From Wikipedia, the free encyclopedia
Giant condyloma acuminatum (also known as a Buschke–Löwenstein tumor[1]) is a rare cutaneous condition characterized by an aggressive, wart-like growth that is a verrucous carcinoma.[2]: 409 It is attributed to human papillomavirus.[3]
| Giant condyloma acuminatum | |
|---|---|
| Other names | Giant condyloma of Buschke–Löwenstein tumor |
| |
| Man, aged 63, with a massive cauliflower-like penile mass with several urinary fistulae making the penile shaft indistinguishable. | |
| Specialty | Infectious diseases |
Due to their size, these tumors can be locally invasive and destructive. Owing to their impressive growth patterns, Buschke-Löwenstein tumors displace and destroy adjacent structures from compression.[4] In general these masses are benign, but the potential for malignant transformation to squamous cell carcinoma exists in the long term, as does the rare risk for metastasis.[5][6][7][8] Buschke-Löwensteoin tumors are frequently associated with HPV subtypes 6 and 11.[4]
Treatment involves surgical resection and possible chemoradiotherapy.[6][8][7] Although penile sparing is the goal, total penectomy may be required. They have high recurrence rates; therefore, close follow-up is crucial.[4]
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References
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