Genomoviridae

Genomoviridae is a family of single stranded DNA viruses that mainly infect fungi.^[1] The genomes of this family are small (2.2–2.4 kilobases in length). The genomes are circular single-stranded DNA and encode rolling-circle replication initiation proteins (Rep) and unique capsid proteins. In Rep-based phylogenies, genomoviruses form a sister clade to plant viruses of the family Geminiviridae.^[2][3] Ten genera are recognized in this family.^[4][5]

Genomoviridae
Virus classification
(unranked):	Virus
Realm:	Monodnaviria
Kingdom:	Shotokuvirae
Phylum:	Cressdnaviricota
Class:	Repensiviricetes
Order:	Geplafuvirales
Family:	Genomoviridae

The family name is an acronym derived from geminivirus-like, no movement protein.^[2]

The genus name Gemycircularvirus stands for Gemini-like myco-infecting circular virus.^[6][7] Sclerotinia sclerotiorum hypovirulence associated DNA virus 1 (ssHADV-1), of the genus Gemycircularvirus, was the first cultivated member of the family.^[2][5] Most other genomoviruses are uncultivated and have been discovered using metagenomics techniques, although more genomoviruses are being isolated as interest grows.^[1][3][8]

Taxonomy

The genera in this family are:^[4]

• Gemycircularvirus
• Gemyduguivirus
• Gemygorvirus
• Gemykibivirus
• Gemykolovirus
• Gemykrogvirus
• Gemykroznavirus
• Gemytondvirus
• Gemytripvirus
• Gemyvongvirus

Virology

Genome map of ssHADV-1

These viruses have circular single-stranded genomes of 2.1–2.2 kilobases in length. All but one genomovirids contain monopartite genomes, whereas the genome of Fusarium graminearum gemytripvirus 1 (genus Gemytripvirus) consists of three segments.^[1] The monopartite genomes encode two proteins—a Rep (replicator) and a CP (capsid) protein. The Rep protein is most closely similar to the Rep protein of the Geminiviridae. In contrast, the CP protein shows no homology to the CP of geminiviruses.^[2]