GSG2

Serine/threonine-protein kinase haspin is an enzyme that in humans is encoded by the GSG2 gene.^[5]

HASPIN
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2VUW, 2WB8, 3DLZ, 3E7V, 3F2N, 3FMD, 3IQ7, 4OUC, 4QTC, 5HTC, 5HTB
Identifiers
Aliases	HASPIN, GSG2, germ cell associated 2, haspin, histone H3 associated protein kinase
External IDs	OMIM: 609240; MGI: 1194498; HomoloGene: 49236; GeneCards: HASPIN; OMA:HASPIN - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.2 Start 3,723,903 bp[1] End 3,726,699 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B4|11 45.25 cM Start 73,026,311 bp[2] End 73,029,120 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell secondary oocyte ventricular zone testicle tibialis anterior muscle ganglionic eminence bone marrow cells sperm mucosa of ileum stromal cell of endometrium Top expressed in spermatid seminiferous tubule spermatocyte zygote primary oocyte secondary oocyte tail of embryo genital tubercle primitive streak epiblast More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity nucleotide binding kinase activity protein serine/threonine kinase activity protein binding histone kinase activity (H3-T3 specific) ATP binding protein kinase activity Cellular component cytoplasm centrosome chromosome cytoskeleton nucleus spindle Biological process intracellular signal transduction phosphorylation mitotic sister chromatid cohesion protein localization to chromosome, centromeric region cell cycle protein phosphorylation chromatin organization mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83903 14841 Ensembl ENSG00000177602 ENSMUSG00000050107 UniProt Q8TF76 Q9Z0R0 RefSeq (mRNA) NM_031965 NM_010353 RefSeq (protein) NP_114171 NP_034483 Location (UCSC) Chr 17: 3.72 – 3.73 Mb Chr 11: 73.03 – 73.03 Mb PubMed search [3] [4]
Wikidata
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