GRAM domain

The GRAM domain is found in glucosyltransferases, myotubularins and other membrane-associated proteins.^[1] The structure of the GRAM domain is similar to that found in PH domains.^[2]

GRAM domain
Myotubularin-related protein 2
Identifiers
Symbol	GRAM
Pfam	PF02893
Pfam clan	CL0266
InterPro	IPR004182
SMART	GRAM
SCOP2	1lw3 / SCOPe / SUPFAM
OPM superfamily	130
OPM protein	1zvr
CDD	cd10570
Membranome	349
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Proteins containing GRAM domains are found in all eukaryotes and bacteria, but not archaea.^[3] Various GRAM domains can bind proteins or lipids.^[3]

Human proteins containing this domain

GRAMD1A; GRAMD1B; GRAMD1C; GRAMD2A; GRAMD2B; GRAMD4; MTM1; MTMR1; MTMR2; NCOA7; NSMAF; OXR1; SBF1; SBF2; TBC1D8; TBC1D8B; TBC1D9; TBC1D9B; WBP2; WBP2NL; dJ439F8.1;