Furanomycin

Furanomycin^[1] is an isoleucine—tRNA ligase inhibitor.^[2]

Furanomycin

Names
Systematic IUPAC name (S)-Amino[(2R,5S)-5-methyl-2,5-dihydrofuran-2-yl]acetic acid
Identifiers
CAS Number	18455-25-9 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:79390 N
ChemSpider	66136 N
PubChem CID	73423
UNII	218WD6K9H0 Y
InChI InChI=1S/C7H11NO3/c1-4-2-3-5(11-4)6(8)7(9)10/h2-6H,8H2,1H3,(H,9,10)/t4-,5+,6-/m0/s1 N Key: PNOKUGWGMLEAPE-JKUQZMGJSA-N N InChI=1/C7H11NO3/c1-4-2-3-5(11-4)6(8)7(9)10/h2-6H,8H2,1H3,(H,9,10)/t4-,5+,6-/m0/s1 Key: PNOKUGWGMLEAPE-JKUQZMGJBF
SMILES C[C@H]1C=C[C@@H](O1)[C@@H](C(=O)O)N
Properties
Chemical formula	C7H11NO3
Molar mass	157.169 g·mol−1
Density	1.238 g/mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

References

1. Katagiri, Ken; Tori, Kazuo; Kimura, Yasuo; Yoshida, Tadashi; Nagasaki, Tohru; Minato, Hitoshi (1967). "A New Antibiotic. Furanomycin, an Isoleucine Antagonist". Journal of Medicinal Chemistry. 10 (6): 1149–1154. doi:10.1021/jm00318a035. PMID 4861779.
2. Tanaka K, Tamaki M, Watanabe S (November 1969). "Effect of furanomycin on the synthesis of isoleucyl-tRNA". Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 195 (1): 244–245. doi:10.1016/0005-2787(69)90621-2. PMID 4982424.