Fotretamine

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Fotretamine

Fotretamine (INNTooltip International Nonproprietary Name), also known as fotrin, is an alkylating antineoplastic and immunosuppressant.[1][2] The drug entered clinical trials in the Soviet Union.[3] It was first described in the literature by 1972.[1][2]

Quick Facts Clinical data, Other names ...
Fotretamine
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Clinical data
Other namesFotrin; Photrin; 2,2,4,4,6-Pentaethyleneimino-6-morpholino-cyclotriphosphazatriene
Drug classAlkylating antineoplastic agent; Immunosuppressant
Identifiers
  • 4-[2,4,4,6,6-pentakis(aziridin-1-yl)-1,3,5-triaza-2λ5,4λ5,6λ5-triphosphacyclohexa-1,3,5-trien-2-yl]morpholine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H28N9OP3
Molar mass431.361 g·mol−1
3D model (JSmol)
  • C1CN1P2(=NP(=NP(=N2)(N3CC3)N4CCOCC4)(N5CC5)N6CC6)N7CC7
  • InChI=1S/C14H28N9OP3/c1-2-18(1)25(19-3-4-19)15-26(20-5-6-20,21-7-8-21)17-27(16-25,22-9-10-22)23-11-13-24-14-12-23/h1-14H2
  • Key:SCGZIPCHOAVGCL-UHFFFAOYSA-N
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