FAM127A

CAAX box protein 1 is a protein that in humans is encoded by the FAM127A gene.^[5][6][7][8]

RTL8C
Identifiers
Aliases	RTL8C, CXX1, MAR8C, MART8C, Mar8, Mart8, FAM127A, family with sequence similarity 127 member A, SIRH5, retrotransposon Gag like 8C
External IDs	OMIM: 300213; MGI: 1920115; HomoloGene: 124163; GeneCards: RTL8C; OMA:RTL8C - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq26.3 Start 135,032,355 bp[1] End 135,033,546 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X A5 Start 52,609,999 bp[2] End 52,610,399 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 10 frontal pole right frontal lobe Hypothalamus cingulate gyrus anterior cingulate cortex apex of heart Amygdala nucleus accumbens left ventricle Top expressed in Hypothalamus striatum of neuraxis adrenal gland Cortex of frontal lobe cerebellar cortex olfactory bulb superior frontal gyrus hippocampus proper primary visual cortex lens More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component membrane plasma membrane cellular component Biological process biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8933 72865 Ensembl ENSG00000134590 ENSMUSG00000051851 UniProt O15255 Q9D6I0 RefSeq (mRNA) NM_003928 NM_001078171 NM_028375 RefSeq (protein) NP_001071639 NP_082651 Location (UCSC) Chr X: 135.03 – 135.03 Mb Chr X: 52.61 – 52.61 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000134590 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051851 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Frattini A, Faranda S, Zucchi I, Vezzoni P (Jan 1998). "A low-copy repeat in Xq26 represents a novel putatively prenylated protein gene (CXX1) and its pseudogenes (DXS9914, DXS9915, and DXS9916)". Genomics. 46 (1): 167–9. doi:10.1006/geno.1997.5006. PMID 9403077.
6. Brandt J, Schrauth S, Veith AM, Froschauer A, Haneke T, Schultheis C, Gessler M, Leimeister C, Volff JN (Apr 2005). "Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals". Gene. 345 (1): 101–11. doi:10.1016/j.gene.2004.11.022. PMID 15716091.
7. Brandt J, Veith AM, Volff JN (Aug 2005). "A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes". Cytogenet Genome Res. 110 (1–4): 307–17. doi:10.1159/000084963. PMID 16093683. S2CID 38398479.
8. "Entrez Gene: FAM127A family with sequence similarity 127, member A".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.