Ethanesulfonic acid

Ethanesulfonic acid (esylic acid) is a sulfonic acid with the chemical formula CH₃CH₂SO₃H. The conjugate base is known as ethanesulfonate or, when used in pharmaceutical formulations, as esilate. It is a colorless liquid.^[2]

Ethanesulfonic acid

Ethanesulfonic acid 3D Ethanesulfonic acid 3D bonds
Names
Preferred IUPAC name Ethanesulfonic acid
Other names Esylic acid, ethylsulfonic acid
Identifiers
CAS Number	594-45-6 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:42465 Y
ChemSpider	11178 N
ECHA InfoCard	100.008.950
EC Number	209-843-0
PubChem CID	11668
UNII	599310E3U2 Y
CompTox Dashboard (EPA)	DTXSID5060487
InChI InChI=1S/C2H6O3S/c1-2-6(3,4)5/h2H2,1H3,(H,3,4,5) InChI=1S/C2H6O3S/c1-2-6(3,4)5/h2H2,1H3,(H,3,4,5) Key: CCIVGXIOQKPBKL-UHFFFAOYSA-N
SMILES CCS(O)(=O)=O
Properties
Chemical formula	C2H6O3S
Molar mass	110.13 g/mol
Appearance	Colorless liquid
Density	1.35 g/mL
Melting point	−17 °C (1 °F; 256 K)
Boiling point	122–123 °C (252–253 °F; 395–396 K) at 0.01 mmHg
Solubility in water	Soluble
log P	−0.37
Acidity (pKa)	−1.68[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

References

1. YK Ye & RW Stringham (2001-06-21). "Effect of mobile phase acidic additives on enantioselectivity for phenylalanine analogs". J Chromatogr A. 927 (1–2): 53–60. doi:10.1016/S0021-9673(01)01059-7. PMID 11572398.
2. Kosswig K, ed. (2000). "Sulfonic Acids, Aliphatic". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a25_503. ISBN 978-3527306732.

External links

• Ye YK, Stringham RW (2006), The effect of acidic and basic additives on the enantioseparation of basic drugs using polysaccharide-based chiral stationary phases. Chirality 18, 519–530. (PubMed:16676332)
• National Center for Biotechnology Information (2005), Ethanesulfonic acid, PubChem Compound Database; CID=11668, (accessed December 23, 2016)
• https://www.scbt.com/scbt/product/ethanesulfonic-acid-594-45-6
• http://www.chemicalbook.com/productmsdsdetailcb5173859_en.htm