Enteric glia

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Enteric glia

The enteric glia, enteric glial cells or EGCs are a population of neuroglial cells that populate the enteric nervous system.[1]

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These cells are one of the major neural-crest-derived cell lineages, found throughout the gastrointestinal tract. The enteric glial cells play a variety of roles, such as modulating nociception (pain sensation), exerting immune functions, and coordingating gastrointestinal motility.[1][2][3] They are the largest glial population outside the brain, and considered "a key node of the gut-brain axis".[4]

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