Dyspropterin

Dyspropterin (6-pyruvoyltetrahydropterin, 6-PTHB) is an intermediate in tetrahydrobiopterin biosynthesis. It is the product of the enzyme 6-pyruvoyltetrahydropterin synthase and the substrate of two enzymes, 6-pyruvoyltetrahydropterin 2'-reductase and sepiapterin reductase.

Dyspropterin

Names
Preferred IUPAC name 1-(2-Amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)propane-1,2-dione
Systematic IUPAC name 1-(2-Amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)propane-1,2-dione
Other names 6-Pyruvoyltetrahydropterin; 6-PTHB
Identifiers
CAS Number	89687-39-8
3D model (JSmol)	Interactive image
3DMet	B05093
Abbreviations	6-PTHB
ChEBI	CHEBI:17804
ChemSpider	559118 (6R) 114280
KEGG	C03684
MeSH	Dyspropterin
PubChem CID	644062 (6R) 128973 ()
UNII	M99D3F9HQF Y
CompTox Dashboard (EPA)	DTXSID601028813
InChI InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h4,12H,2H2,1H3,(H4,10,11,13,14,17) Key: WBJZXBUVECZHCE-UHFFFAOYSA-N
SMILES CC(=O)C(=O)C1CNC2=C(N1)C(=O)N=C(N)N2
Properties
Chemical formula	C9H11N5O3
Molar mass	237.219 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Dyspropterin exists in all living organisms, ranging from bacteria to humans.^[1] Dyspropterin has been detected, but not quantified in, a few different foods, such as ducks (Anatidae), chickens (Gallus gallus), and domestic pigs (Sus scrofa domestica).^[2] This could make dyspropterin a potential biomarker for the consumption of these foods.^[3]

See also

• Tetrahydrobiopterin

References

1. "Showing Compound Dyspropterin (FDB022481) - FooDB". foodb.ca. Retrieved 2022-03-30.
2. "Showing Compound Dyspropterin (FDB022481) - FooDB". foodb.ca. Retrieved 2022-03-30.
3. "Showing Compound Dyspropterin (FDB022481) - FooDB". foodb.ca. Retrieved 2022-03-30.