Dinotefuran

Dinotefuran
Names
	IUPAC name 2-methyl-1-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine
	Other names (RS)-1-methyl-2-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine; MTI-446
Identifiers
CAS Number	165252-70-0 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:39183 ;
ChemSpider	171124 ;
ECHA InfoCard	100.111.831
KEGG	C18509 ;
PubChem CID	197701;
UNII	1W509710WF ;
CompTox Dashboard (EPA)	DTXSID7034549 ;
	InChI InChI=1S/C7H14N4O3/c1-8-7(10-11(12)13)9-4-6-2-3-14-5-6/h6H,2-5H2,1H3,(H2,8,9,10) Key: YKBZOVFACRVRJN-UHFFFAOYSA-N ;
	SMILES [O-][N+](=O)NC(=N/C)\NCC1CCOC1;
Properties
Chemical formula	C7H14N4O3
Molar mass	202.214 g·mol−1
Melting point	107.5
Solubility in water	39.83 g/L
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	≥2000 mg/kg (oral, rat and mouse)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Dinotefuran is an insecticide of the neonicotinoid class developed by Mitsui Chemicals for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers, sawflies, mole cricket, white grubs, lacebugs, billbugs, beetles, mealybugs, and cockroaches on leafy vegetables, in residential and commercial buildings, and for professional turf management.^[2] Its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.

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In July 2013, the US state of Oregon temporarily restricted the use of dinotefuran pending the results of an investigation into a large bee kill.^[3]

Dinotefuran is also used in veterinary medicine as a flea and tick preventive for dogs and as a flea preventive for cats. It is used in combination with pyriproxifen and/or permethrin.^[4]^[5]

Studies show dinotefuran is effective at controlling the invasive Spotted lanternfly, first found in Berks County, PA, in 2014. ^[6]

Research