Dimefox

Dimefox
Names
	IUPAC name N-[dimethylamino(fluoro)phosphoryl]-N-methylmethanamine
	Other names TL-792; T-2002
Identifiers
CAS Number	115-26-4 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:82119 ;
ChemSpider	7966 ;
ECHA InfoCard	100.003.706
EC Number	204-076-8;
KEGG	C18980 ;
PubChem CID	8264;
UNII	N8RU9F1IQD ;
CompTox Dashboard (EPA)	DTXSID8041870 ;
	InChI InChI=1S/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3 Key: PGJBQBDNXAZHBP-UHFFFAOYSA-N ; InChI=1/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3 Key: PGJBQBDNXAZHBP-UHFFFAOYAM;
	SMILES CN(C)P(=O)(N(C)C)F;
Properties
Chemical formula	C4H12FN2OP
Molar mass	154.125 g·mol−1
Appearance	colourless liquid
Density	1.11 g·mL–1
Solubility in water	14.8 g·L–1
Vapor pressure	14663 mPa
Henry's law; constant (kH)	2.28·10–8 atm·m3·mol–1
Pharmacology
Routes of; administration	inhalation and dermal contact
Legal status	UK: Banned; US: Banned;
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Highly Toxic
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H300, H310
Precautionary statements	P262, P264, P270, P280, P301+P310, P302+P350, P310, P321, P322, P330, P361, P363, P405, P501
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	2 mg/kg (oral, mice); 1 mg/kg (oral, rats); 3 mg/kg (intravenous, rabbits)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Dimefox, also known as TL-792 or T-2002, is a highly toxic organophosphate insecticide. In its pure form it is a colourless liquid with a fishy odour.^[3] Dimefox was first produced in 1940 by the group of Gerhard Schrader in Germany. It was historically used as a pesticide, but has been deemed obsolete or discontinued for use by the World Health Organization due to being an inhibitor of acetylcholinesterase.^{[citation needed]} It is not guaranteed that all commercial use of this compound ceased, but in most countries^[which?] it is no longer registered for use as a pesticide.^[4] It is considered an extremely hazardous substance as defined by the United States Emergency Planning and Community Right-to-Know Act.

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[1]
Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
[2]
"Dimefox".
[3]
"IUPAC FOOTPRINT Pesticides Properties Database". Archived from the original on 2011-07-22. Retrieved 2011-04-06.
[4]
the WHO recommended classification of pesticides by hazard and guidelines to classification 2009,

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See also

Names


IUPAC name N-[dimethylamino(fluoro)phosphoryl]-N-methylmethanamine
Other names TL-792^[1] T-2002^[1]
Identifiers
CAS Number	115-26-4^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:82119^Y
ChemSpider	7966^Y
ECHA InfoCard	100.003.706
EC Number	204-076-8
KEGG	C18980^Y
PubChem CID	8264
UNII	N8RU9F1IQD^Y
CompTox Dashboard (EPA)	DTXSID8041870
InChI InChI=1S/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3^N Key: PGJBQBDNXAZHBP-UHFFFAOYSA-N^N InChI=1/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3 Key: PGJBQBDNXAZHBP-UHFFFAOYAM
SMILES CN(C)P(=O)(N(C)C)F
Properties
Chemical formula	C₄H₁₂FN₂OP
Molar mass	154.125 g·mol⁻¹
Appearance	colourless liquid
Density	1.11 g·mL^–1
Solubility in water	14.8 g·L^–1
Vapor pressure	14663 mPa
Henry's law constant (k_H)	2.28·10^–8 atm·m³·mol^–1^[2]
Pharmacology
Routes of administration	inhalation and dermal contact
Legal status	UK: Banned US: Banned
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Highly Toxic
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H300, H310
Precautionary statements	P262, P264, P270, P280, P301+P310, P302+P350, P310, P321, P322, P330, P361, P363, P405, P501
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	2 mg/kg (oral, mice)^[1] 1 mg/kg (oral, rats)^[1] 3 mg/kg (intravenous, rabbits)^[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references