DOTAM

DOTAM (also known as TCMC) is an organic compound used as a chelator much like its carboxylic acid analog DOTA. A derivative with a reactive linking group of para-isothiocyanatobenzyl attached to the cyclen ring is also of interest as a bifunctional chelator (BFC).^[1][2]

p-SCN-Bn-DOTAM

DOTAM

Names
IUPAC name 2-[4,7,10-tris(2-amino-2-oxoethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetamide
Other names TCMC 2,2′,2”,2”’-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetamide 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic amide 1,4,7,10-tetraaza-1,4,7,10-tetra(2-carbamoylmethyl)cyclododecane
Identifiers
CAS Number	157599-02-5
3D model (JSmol)	Interactive image
ChemSpider	9735169
PubChem CID	11560395
CompTox Dashboard (EPA)	DTXSID90468610
InChI Key: FQIHLPGWBOBPSG-UHFFFAOYSA-N InChI=1S/C16H32N8O4/c17-13(25)9-21-1-2-22(10-14(18)26)5-6-24(12-16(20)28)8-7-23(4-3-21)11-15(19)27/h1-12H2,(H2,17,25)(H2,18,26)(H2,19,27)(H2,20,28)
SMILES NC(CN1CCN(CC(N)=O)CCN(CC(N)=O)CCN(CC(N)=O)CC1)=O
Properties
Chemical formula	C16H32N8O4
Molar mass	400.484 g·mol−1
Appearance	White powder
Solubility in water	Soluble (hygroscopic)
Hazards
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H315, H319, H335
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references