Concentrative nucleoside transporter

Human concentrative nucleoside transporters include SLC28A1, SLC28A2 and SLC28A3 proteins. SLC28A2 is a purine-specific Na⁺-nucleoside cotransporter localised to the bile canalicular membrane.^[1] SLC28A1 is a Na⁺-dependent nucleoside transporter selective for pyrimidine nucleosides and adenosine. It also transports the anti-viral nucleoside analogues Zidovudine and Zalcitabine.^[2]

Nucleos_tra2_C
Identifiers
Symbol	Nucleos_tra2_C
Pfam	PF07662
InterPro	IPR011657
TCDB	2.A.41
OPM superfamily	388
OPM protein	3tij
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

References

1. Che M, Ortiz DF, Arias IM (Jun 1995). "Primary structure and functional expression of a cDNA encoding the bile canalicular, purine-specific Na(+)-nucleoside cotransporter". The Journal of Biological Chemistry. 270 (23): 13596–9. doi:10.1074/jbc.270.23.13596. PMID 7775409.
2. Huang QQ, Yao SY, Ritzel MW, Paterson AR, Cass CE, Young JD (Jul 1994). "Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein". The Journal of Biological Chemistry. 269 (27): 17757–60. doi:10.1016/S0021-9258(17)32370-0. PMID 8027026.

This article incorporates text from the public domain Pfam and InterPro: IPR011657