Clomifenoxide

Clomifenoxide (INN), also known as clomifene N-oxide, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that is described as an antiestrogen and "gonad stimulant" and was never marketed.^[1][2] It is an active metabolite of clomifene.^[3][4]

Clomifenoxide

Clinical data
Other names	Clomifene N-oxide
Identifiers
IUPAC name (E,Z)-2-(p-(2-Chloro-1,2-diphenylvinyl)phenoxy)triethylamine N-oxide
CAS Number	97642-74-5
PubChem CID	9979613
ChemSpider	8155205
UNII	L88W2ZR0TI
CompTox Dashboard (EPA)	DTXSID70869303
Chemical and physical data
Formula	C26H28ClNO2
Molar mass	421.97 g·mol−1
3D model (JSmol)	Interactive image
SMILES [N+](CCOc1ccc(cc1)C(=C(/c1ccccc1)Cl)\c1ccccc1)(CC)(CC)[O-]
InChI InChI=1S/C26H28ClNO2/c1-3-28(29,4-2)19-20-30-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3/b26-25- Key:PGHWCZITRQNIPM-QPLCGJKRSA-N

See also

• Afimoxifene
• Endoxifen

References

1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 298–. ISBN 978-1-4757-2085-3.
2. Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 3506. ISBN 978-3-527-30247-5.
3. Analytical Profiles of Drug Substances and Excipients. Academic Press. 20 March 1998. pp. 113–. ISBN 978-0-08-086120-3.
4. Goodwin BL (10 November 2004). Handbook of Biotransformations of Aromatic Compounds. CRC Press. pp. 3–. ISBN 978-0-203-64196-5.