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Ciliary body melanoma is a type of cancer arising from the coloured part (uvea) of the eye.
 | This article includes a list of references, related reading, or external links, but its sources remain unclear because it lacks inline citations. (June 2014) |
About 12% of uveal melanoma arise from the ciliary body.
It occurs most commonly in the sixth decade of life.
- External signs include dilated episcleral blood vessels (sentinel vessels). Extraocular erosion may produce a dark mass beneath the conjunctiva.
- Pressure on the lens by the enlarging tumor can cause astigmatism, subluxation of the lens and formation of a localised lens opacity.
- The tumor can erode forward through the iris root and mimic an iris melanoma.
- Retinal detachment can be rarely caused by posterior extension of the tumor.
- Anterior uveitis is an uncommon presentation and occurs due to tumor necrosis.
- Cirumferentially growing tumors carry a bad prognosis as they are diagnosed late.
- At times the tumor is detected as an incidental finding during routine examination.
The tumour is usually diagnosed by clinical examination with a slit-lamp utilising a triple mirror contact lens. Ultrasonography and fine-needle aspiration biopsy (FNAB) are also sometimes helpful in confirming the diagnosis.
Enucleation (surgical removal of the eye) is the treatment of choice for large ciliary body melanomas. Small or medium sized tumors may be treated by an iridocyclectomy. Radiotherapy may be appropriate in selected cases.
- Ocular oncology
- Uveal melanoma – melanoma of the eye
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