Cetrimonium chloride

Cetrimonium chloride, or cetyltrimethylammonium chloride (CTAC), is a topical antiseptic and surfactant. Long-chain quaternary ammonium surfactants, such as cetyltrimethylammonium chloride (CTAC), are generally combined with long-chain fatty alcohols, such as stearyl alcohols, in formulations of hair conditioners and shampoos.^[1][2] The cationic surfactant concentration in conditioners is generally of the order of 1–2% and the alcohol concentrations are usually equal to or greater than those of the cationic surfactants. The ternary system, surfactant/fatty alcohol/water, leads to a lamellar structure forming a percolated network giving rise to a gel. ^[2]

Cetrimonium chloride

Names
Preferred IUPAC name N,N,N-Trimethylhexadecan-1-aminium chloride
Identifiers
CAS Number	112-02-7 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:53581 Y
ChemSpider	7862 Y
ECHA InfoCard	100.003.571
PubChem CID	8154
UNII	UC9PE95IBP Y
CompTox Dashboard (EPA)	DTXSID6026901
InChI InChI=1S/C19H42N.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1 Y Key: WOWHHFRSBJGXCM-UHFFFAOYSA-M Y InChI=1/C19H42N.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1 Key: WOWHHFRSBJGXCM-REWHXWOFAY
SMILES CCCCCCCCCCCCCCCC[N+](C)(C)C.[Cl-]
Properties
Chemical formula	C19H42ClN
Molar mass	320.00 g/mol
Pharmacology
ATC code	D08AJ02 (WHO) R02AA17 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

See also

• Behentrimonium chloride – an C₂₅ structural analogue
• Cetrimonium bromide – the corresponding bromide salt

References

1. What is cetrimonium chloride? Archived 2012-03-04 at the Wayback Machine at naturallycurly.com
2. "The cooling process effect on the bilayer phase state of the CTAC/cetearyl alcohol/water surfactant gel", Colloids and Surfaces A 597 (2020) 1248212