CTDSP1

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 is an enzyme that in humans is encoded by the CTDSP1 gene.^[5][6][7]

CTDSP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1T9Z, 1TA0, 2GHQ, 2GHT, 3L0B, 3L0C, 3L0Y, 3PGL, 4YGY, 4YH1
Identifiers
Aliases	CTDSP1, NIF3, NLI-IF, NLIIF, SCP1, CTD small phosphatase 1
External IDs	OMIM: 605323; MGI: 2654470; HomoloGene: 100834; GeneCards: CTDSP1; OMA:CTDSP1 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q35 Start 218,398,256 bp[1] End 218,405,941 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C3 Start 74,430,668 bp[2] End 74,436,444 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte right coronary artery gastric mucosa body of stomach Descending thoracic aorta apex of heart left uterine tube right ovary canal of the cervix popliteal artery Top expressed in granulocyte urinary bladder adrenal gland white adipose tissue muscle tissue muscle of thigh human kidney lip skeletal muscle tissue esophagus More reference expression data BioGPS n/a
Gene ontology Molecular function phosphatase activity RNA polymerase II CTD heptapeptide repeat phosphatase activity protein binding phosphoprotein phosphatase activity hydrolase activity metal ion binding Cellular component extracellular exosome nucleus nucleoplasm Biological process regulation of transcription by RNA polymerase II negative regulation of G1/S transition of mitotic cell cycle negative regulation of protein phosphorylation negative regulation of neurogenesis protein dephosphorylation negative regulation of neuron differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 58190 227292 Ensembl ENSG00000144579 ENSMUSG00000026176 UniProt Q9GZU7 P58466 RefSeq (mRNA) NM_001206878 NM_001206879 NM_021198 NM_182642 NM_153088 RefSeq (protein) NP_001193807 NP_067021 NP_872580 NP_694728 Location (UCSC) Chr 2: 218.4 – 218.41 Mb Chr 1: 74.43 – 74.44 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

CTDSP1 has been shown to interact with SNAI1.^[8]