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Protein-coding gene in humans From Wikipedia, the free encyclopedia
C-type lectin domain family 1 member A is a protein that in humans is encoded by the CLEC1A gene.[5][6][7]
CLEC1A | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | CLEC1A, CLEC-1, CLEC1, C-type lectin domain family 1 member A | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 606782; MGI: 2444151; HomoloGene: 9549; GeneCards: CLEC1A; OMA:CLEC1A - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. Alternative splice variants have been described but their biological nature has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.[7]
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